C-Reactive Protein, Quantitative (CRP)

Code

1536

Principle

CRP is synthesized in the liver and released into the circulatory system in response to proinflammatory stimuli, the strongest of which is interleukin-6 (IL-6). It is this positive response to inflammation from which CRP derives its diagnostic utility and categorizes it with “acute phase reactants”. CRP has been called the archetype of acute phase proteins due to its rapid (24 to 28 hours) and marked response to a wide variety of inflammatory conditions and diseases. These stimuli include bacterial and fungal components, as well as damaged cell membranes from injured tissue arising from trauma, arthritis, vasculitides, and a spectrum of autoimmune processes.

Preanalytical

1 mL Serum Refrigerated

Turn Around Time

1 day

Methodology

Immunoturbidimetric