Cancer Ag, 15-3




The CA 15-3 antigen is an epitope on a large mucin-like glycoprotein, which is a product of MUCI Mucins, present in normal glandular epithelia of various organs , serve to protect and lubricate surrounding cells. In breast cancer, the MUCI mucin becomes aberrantly glycosylated, overexpressed and released into circulation, it may be detected at elevated levels. CA 15-3 antigen levels are elevated in may patients with epithelial breast carcinoma. Elevated levels of CA 15-3 antigen may also be present in those patients with lung, ovarian, pancreatic and colorectal cancers, as well as non-malignant conditions including benign breast and liver disease, cirrhosis, and hepatitis.


1 mL Serum Refrigerated

Turn Around Time

1 day


Chemiluminescent immunoassay (CLIA)


Patients who have been regularly exposed to animals or have received immunotherapy or diagnostic procedures utilizing immunoglobulins or immunoglobulin fragments may produce antibodies, e.g. HAMA, that interfere with immunoassays.

All results should be interpreted in light of the total clinical presentation of the patient, including: symptoms, clinical history, data from additional tests and other appropriate information.