Growth Hormone (GH)

Code

2705

Principle

Human growth hormone is a 191-amino acid, single chain polypeptide hormone is synthesized, stored and secreted by somatotroph cells located predominantly in the lateral wings of the anterior pituitary gland. Serum hGH concentrations exhibit marked variation in the course of 24 hours as a result of episodic bursts or pulses of hGH secretion and prominent circadian and sleep-associated variations in hGH release.2 Additionally, numerous
environmental and metabolic factors including (but not limited to) nutrient intake, exercise, physical stress or exercise, depression, trauma, and age, influence secretion and clearance of hGH and therefore influence the concentration existing in serum.

Preanalytical

1 mL Serum Refrigerated

Turn Around Time

2 days

Methodology

Chemiluminescent immunoassay (CLIA)

Limitations

Patients who have been regularly exposed to animals or have received immunotherapy or diagnostic procedures utilizing immunoglobulins or immunoglobulin fragments may produce antibodies, e.g. HAMA, that interfere with immunoassays.

All results should be interpreted in light of the total clinical presentation of the patient, including: symptoms, clinical history, data from additional tests and other appropriate information.