Protein, Serum

Code

5190

Principle

Proteins derive primarily from synthesis in the liver, plasma cells, lymph nodes, spleen, and bone marrow. In disease states both the total plasma protein level and the ratio of the individual fractions may be dramatically altered from their normal values. Hypoproteinemia may be caused by such conditions as nephrotic syndrome, extensive bleeding, sprue (deficient protein absorption), severe burns, salt retention syndromes, and Kwashiorkor (acute protein starvation). Hyperproteinemia may be observed in cases of severe dehydration and disease states such as multiple myeloma.

Preanalytical

1 mL Serum Refrigerated

Turn Around Time

1 day

Methodology

Biuret