Thyroid Stimulating Hormone (TSH)

Code

5945

Principle

Human thyroid-stimulating hormone is a glycoprotein hormone consisting of two noncovalently-bound subunits: an α subunit, which is nearly identical to the α subunits of human luteinizing hormone (hLH), human follicle-stimulating hormone (hFSH), and human chorionic gonadotropin (hCG), and a β subunit, which is responsible for immunological and biological specificity.

Preanalytical

1 mL Serum Refrigerated

Turn Around Time

1 day

Methodology

Chemiluminescent immunoassay (CLIA)

Limitations

Patients who have been regularly exposed to animals or have received immunotherapy or diagnostic procedures utilizing immunoglobulins or immunoglobulin fragments may produce antibodies, e.g. HAMA, that interfere with immunoassays.